Endothelial Microparticles and Platelet and Leukocyte Activation in Patients With the Metabolic Syndrome 内皮细胞微粒与代谢综合征患者血小板和白细胞的激活
Objective To study the relationship between the soluble endothelial leukocyte adhesion molecules ( sELAM 1) in serum and allergic skin diseases. 目的分析血清中可溶性内皮细胞白细胞粘附分子(sELAM1)含量变化与过敏性皮肤病发病的关系。
Aim: To investigate the expression of endothelial leukocyte adhesion molecule 1 ( ELAM 1) mRNA and intercellular adhesion molecule 1 ( ICAM 1) mRNA in pulmonary vascular endothelial cell ( VEC) in endotoxin induced acute lung injury. 目的:为观察内毒素性急性肺损伤肺血管内皮细胞(VEC)内皮细胞白细胞粘附分子-1(ELAM-1)和细胞间粘附分子-1(ICAM-1)转录水平的表达规律。
Change of Serum Soluble Endothelial Leukocyte Adhesion Molecule 1 in Patients with Cerebral Infarction 脑梗死血清可溶性内皮细胞白细胞粘附分子-1的变化
Effects of Pentoxifylline on Leukocyte Adhering to Endothelial Cell Exercise and change of leukocyte 运动与白细胞的变化
In adipocytes and smooth muscle cells, SSAO activity stimulates glucose transport, mimicking the insulin effect, while in endothelial cells, where it is identical to vascular adhesion protein-1 ( VAP-1), it is involved in leukocyte trafficking and extravasation during inflammation. 脂肪细胞和平滑肌细胞表达的SSAO酶可促进葡萄糖转运,具有类胰岛素效应;而内皮细胞表达的SSAO酶即血管黏附蛋白-1(VAP-1)参与炎症过程中白细胞的运输与外渗。
Interestingly, Slit attracts vascular endothelial cells, which is opposite to its roles as repellents and inhibitors in axon guidance and neuronal and leukocyte migration. 有趣的是,Slit吸引血管内皮细胞运动,这和它作为神经轴突,神经元以及白细胞迁移的排斥因子和抑制因子的作用是相反的。
Mainly expressed in the cell surface of endothelial cells, leukocyte, platelets and smooth muscle, a little exist in plasma in soluble form. 主要表达于内皮细胞、白细胞、血小板及平滑肌细胞表面,少许以可溶性形式存在于血浆中。
Besides, RAGE on endothelial cells may function as an adhesive receptor that interacts with leukocyte p2-integrins, thereby directly being involved in inflammatory cell recruitment. 另外,内皮细胞表面RAGE还可作为黏附受体与白细胞β2整合素作用,直接参与血管壁炎症细胞的募集。